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Evaluate lower respiratory tract infections in young children. Severe life-threatening infections due to respiratory syncytial virus can occur during the first few years. Acquired immunity is incomplete and reinfection can occur later.
A positive result may occur in the absence of viable virus. In the event of a negative result, infection due to RSV cannot be ruled out because the antigen present may be below the detection limit of the test. A negative test is presumptive, and it is recommended by the assay manufacturer that these results be confirmed by another method. Freezing of the sample may also diminish detection of the antigen.
This test allows rapid diagnosis of the presence of respiratory syncytial virus. It avoids the necessity of obtaining acute and convalescent specimens over a two-week period. It may be particularly useful in children younger than six months old, whose antibody response to infection may not be diagnostic.
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