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Diagnose primary or metastatic neoplasm; detect Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis.
Failure to obtain adequate ectocervical, endocervical, or vaginal cell population is suboptimal for evaluation. Excessive use of lubricating jelly on the vaginal speculum will interfere with cytologic examination and may lead to unsatisfactory Pap results.
Testing for Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis requires special procedures to be used in the processing of the cytology specimens; therefore, testing for these organisms cannot be added on after the specimen has been submitted. The liquid-based cytology specimen must be processed for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing.
Any time a transport device used for molecular testing is processed, the chance of cross specimen contamination increases. Aptima® transports can be placed directly on the analyzer, limiting the possibility of cross specimen contamination.
Centers for Disease Control and Prevention. Screening Test to Detect Chlamydia trachomatis and Neisseria gonorrhoeae-2002. MMWR. 2002; 51(RR15). PubMed 12418541
Hutchinson ML, Cassin CM, Harrison GB. The efficacy of an automated preparation device for cervical cytology. Am J Clin Pathol. 1991; 96(3):300-305. PubMed 1877527
Hutchinson ML, Isenstein LM, Goodman A, et al. Homogeneous sampling accounts for the increased diagnostic accuracy uising the ThinPrep® Processor. Am J Clin Pathol. 1994; 101(2):215-219. PubMed 8116578
Joseph MG, Cragg F, Wright VC, et al. Cytohistological correlates in a colposcopic clinic: A 1-year prospective study. Diagn Cytopathol. 1991; 7(5):477-481. PubMed 1954825
van Der Schee C, van Belkum A, Zwijgers L, et al. Improved diagnosis of Trichomonas vaginalis infection by PCR using vaginal swabs and urine specimen compared to diagnosis by wet mount microscopy, culture, and fluorescent staining. J Clin Microbiol. 1999; 37(12):4127-4130. PubMed 10565943
Wilbur DC, Cibas ES, Merritt S, et al. ThinPrep® Processor: Clinical trials demonstrate an increased detection rate of abnormal cervical cytologic specimens. Am J Clin Pathol. 1994; 101(2):209-214. PubMed 8116577
