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Use: 14-3-3 eta protein is a joint-derived, proinflammatory mediator that is implicated in the joint erosion process and pathogenesis of RA. Serum 14-3-3 eta is elevated in both early and established RA.
Limitations: This test was developed, and its performance characteristics were determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Methodology: Enzyme-linked immunosorbent assay (ELISA)
